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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LMNB1 All Species: 25.76
Human Site: T65 Identified Species: 51.52
UniProt: P20700 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20700 NP_005564.1 586 66408 T65 S A L Q L Q V T E R E E V R G
Chimpanzee Pan troglodytes XP_517906 586 66445 T65 S A L Q L Q V T E R E E V R G
Rhesus Macaque Macaca mulatta XP_001097340 586 66435 T65 S A L Q L Q V T E R E E V R G
Dog Lupus familis XP_531892 519 58503 L45 A Q S L A G P L A L F Q I S Y
Cat Felis silvestris
Mouse Mus musculus P14733 588 66767 T66 S A L Q L Q V T E R E E V R G
Rat Rattus norvegicus P70615 587 66588 T65 S A L Q L Q V T E R E E V R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506656 591 66278 A65 M R A K L G K A S W K S Y A K
Chicken Gallus gallus P14731 584 66512 S64 S A L Q R R V S E R E Q V C G
Frog Xenopus laevis P09010 583 66432 T65 S L L H V Q V T E R E E V R S
Zebra Danio Brachydanio rerio NP_694504 588 66732 R66 S V L Q I Q I R E R E D V R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08928 622 71282 Q87 S R L T I E V Q T T R D T V T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21443 566 64066 R78 N R L Q V Q I R D I E V V E K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 81.5 N.A. 95.9 95.4 N.A. 61.2 79.3 72.5 69.3 N.A. 37.6 N.A. 34.1 N.A.
Protein Similarity: 100 100 99.6 84.6 N.A. 97.6 97.4 N.A. 69 89.5 85.8 84.8 N.A. 59.4 N.A. 51.7 N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 6.6 66.6 73.3 60 N.A. 20 N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 20 86.6 80 80 N.A. 40 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 50 9 0 9 0 0 9 9 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 17 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 67 0 75 50 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 50 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 17 0 17 0 0 9 0 0 9 0 0 % I
% Lys: 0 0 0 9 0 0 9 0 0 0 9 0 0 0 17 % K
% Leu: 0 9 84 9 50 0 0 9 0 9 0 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 67 0 67 0 9 0 0 0 17 0 0 0 % Q
% Arg: 0 25 0 0 9 9 0 17 0 67 9 0 0 59 0 % R
% Ser: 75 0 9 0 0 0 0 9 9 0 0 9 0 9 9 % S
% Thr: 0 0 0 9 0 0 0 50 9 9 0 0 9 0 9 % T
% Val: 0 9 0 0 17 0 67 0 0 0 0 9 75 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _